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Catherine Laprise

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Articles

  1. Tremblay BL, Bégin P, Gagnon-Brassard F, Boucher-Lafleur AM, Lavoie MÈ, Madore AM, Lavoie S, Rochefort-Beaudoin C, Nuncio-Naud C, Morin C, Parizeault G, Laprise C. 2024. Zéro allergie research clinic: a clinical and research initiative in oral immunotherapy for managing IgE-mediated food allergy. Allergy Asthma Clin Immunol. 2;20(1):59.
  2. Bchetnia M, Powell J, McCuaig C, Boucher-Lafleur AM, Morin C, Dupérée A, Laprise C. 2024. Pathological mechanisms involved in epidermolysis bullosa simplex: current knowledge and therapeutic perspectives. International Journal of Molecular Sciences. 31;25(17):9495.
  3. Gélinas R, Lévesque C, Thompson-Legault J, Rivard ME, Villeneuve L, Laprise C, Rioux JD. 2024. Human induced pluripotent stem cells (hiPSCs) derived cells reflect tissue specificity found in patients with Leigh syndrome French Canadian variant (LSFC). Frontiers in Genetics. 19(15): 1375467.
  4. Amri O, Madore AM, Boucher-Lafleur AM, Laprise C. 2024. Genomic analysis of severe COVID-19 considering or not asthma comorbidity: GWAS insights from the BQC19 cohort. BMC Genomics, 16;25(1):482.
  5. Gélinas R, Lévesque C, Thompson-Legault J, Rivard ME, Villeneuve L, Laprise C, Rioux JD. 2024. Human induced pluripotent stem cells (hiPSCs) derived cells reflect tissue specificity found in patients with Leigh syndrome French Canadian variant (LSFC). Frontiers in Genetics. 19(15): 1375467.
  6. Gagnon L, Moreau C, Laprise C, Vézina H, Girard SL. 2024. Deciphering the genetic structure of the Quebec founder population using genealogies. Eur J Hum Genet. 32(1): 91-97.
  7. Bourumeau W, Tremblay K, Jourdan G, Girard C, Laprise C. 2023. Bacterial biomarkers of the oropharyngeal and oral cavity during SARS-CoV-2 infection. Microorganisms 11(11): 2703.
  8. Gagnon PA, Klein M, De Vos J, Biardel S, Côté A, Godbout K, Laviolette M, Laprise C, Assou S, Chakir J. 2023. S100A alarmins and thymics stromal lymphopoietin (TSLP) regulation in severe asthma following bronchial thermoplasty. Respir Res. 24(1): 294.
  9. Aoussim A, Légaré C, Roussel MP, Madore AM, Morissette M, Laprise C, Duchesne E. 2023. Towards the identification of biomarkers for muscle function improvement in myotonic dystrophy type 1. Journal of Neuromuscular Diseases, doi: 10.3233/JND-221645.
  10. Herrera-Luis E, de la Rosa-Baez C, Huntsman S, Eng C, Beckman KB, Lenoir MA, Rodriguez-Santana J, Villar J, Laprise C, Borrell LN, Ziv E, Burchard EG, Pino-Yanes M. 2023. Novel insights into the whole blood DNA methylome of asthma in ethnically diverse children and youth. Eur Respir J. 62(6): 2300714.
  11. Margaritte-Jeannin P, Vernet R, Budu-Aggrey A, Ege M, Madore AM, Linhard C, Mohamdi H, von Mutius E, Granell R, Demenais F, Laprise C, Bouzigon E, Dizier MH. 2023. TNS1 and NRXN1 genes interacting with early-life smoking exposure in asthma-plus-eczema susceptibility. Allergy Asthma Immunol Res. 15(6):779-794.
  12. Gagon PA, Klein M, De Vos J, Biardel S, Côté A, Godbout K, Laviolette M, Laprise C*, Assou S*, Chakir J. 2023. S100 A alarmin expression in severe asthma and effect of bronchial thermoplasty. JACI, lettre à l’éditeur sous presse. * contribution égale
  13. Laprise C. 2023. It’s time to take a sustainable approach to health care in the face of the challenges of the 21st century. One Health. 16: 100510.
  14. Rakesh M, Vézina H, Laprise C, Freeman EE, Burkett KM, Roy-Gagnon MH. 2023. GENLIB: New function to simulate haplotype transmission in large complex genealogies. Bioinformatics 17:btad136.
  15. Lavoie ME, Meloche J, Boucher-Lafleur AM, Bégin P, Morin C, Boulet LP, Madore AM, Laprise C. 2022. Longitudinal follow-up of the asthma status in a French-Canadian cohort. Sci Rep. 12(1): 13789.
  16. Bchetnia M, Dionne Gagné R, Powell J, Morin C, McCuaig C, Dupérée A, Germain L, Tremblay JP, Laprise C. 2022. Allele-Specific Inactivation of an Autosomal Dominant Epidermolysis Bullosa Simplex Mutation Using CRISPR-Cas9.CRISPR J. 5(4): 586-597.
  17. Moreau C, Tremblay F, Wolking S, Girard A, Laprise C, Hamdan FF, Michaud JL, Minassian BA, Cossette P, Girard SL. 2022. Assessment of burden and segregation profiles of CNVs in patients with epilepsy. Ann Clin Transl Neurol. 9(7): 1050-1058.
  18. Vernet R, Matran R, Zerimech F, Madore AM, Lavoie ME, Gagnong PA, Mohamdi H, Margaritte-Jeannin P, Siroux V, Dizier MH, Demenais F, Laprise C, Nadif R, Bouzigon E. 2022. Identification of novel genes influencing eosinophil-specific protein levels in asthma families. J Allergy Clin Immunol. 150(5):1168-1177.
  19. Madore AM, Bossé Y, Margaritte-Jeannin P, Vucic E, Lam WL, Bouzigon E, Bourbeau J, Laprise C. 2022. Analysis of GWAS-nominated loci for lung cancer and COPD revealed a new asthma locus. BMC Pulm Med. 22(1): 155.
  20. Bchetnia M, Martineau L, Racine V, Powell J, McCuaig C, Morin C, Dupérée A, Gros-Louis F, Laprise C. 2022. Generation of two induced pluripotent stem cell lines (UQACi002-A and UQACi005-A) from two patients with KRT14 epidermolysis bullosa simplex mutations. Stem Cell Res. 61: 102750.
  21. Bchetnia M, Martineau L, Racine V, Powell J, McCuaig C, Morin C, Dupérée A, Gros-Louis F, LapriseC. 2022. Generation of three induced pluripotent stem cell lines (UQACi003-A, UQACi004-A, and UQACi006-A) from three patients with KRT5 epidermolysis bullosa simplex mutations. Stem Cell Res. 60:102726.
  22. Bchetnia M, Tardif J, Morin C, Laprise C. 2022. Expression signature of the Leigh syndrome French Canadian type. Mol Genet Metab Rep. 30: 10
  23. Burkett KM, Rakesh M, Morris P, Vézina H, Laprise C, Freeman EE, Roy-Gagnon MH. 2022. Correspondence Between Genomic- and Genealogical/Coalescent-Based Inference of Homozygosity by Descent in Large French-Canadian Genealogies.Front Genet.12: 808829.
  24. Bélanger E, Laprise C. 2021. Could the Epigenetics of Eosinophils in Asthma and Allergy Solve Parts of the Puzzle? Int J Mol Sci. 22(16): 8921.
  25. Cuillerier A, Ruiz M, Daneault C, Forest A, Rossi J, Vasam G, Cairns G, Cadete V, LSFC Consortium, Des Rosiers C, Burelle Y. 2021. Adaptive optimization of the OXPHOS assembly line partially compensates lrpprc-dependent mitochondrial translation defects in mice. Commun Biol. 4(1): 989.
  26. Margaritte-Jeannin P, Budu-Aggrey A, Ege M, Madore AM, Linhard C, Mohamdi H, von Mutius E, Granell R, Demenais F, Laprise C, Bouzigon E, Dizier MH. 2021. Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema. Clin Exp Allergy. 52(1): 70-81.
  27. Tremblay K, Rousseau S, Zawati MnH, et al. 2021. The Biobanque québécoise de la COVID-19 (BQC19)-A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories. PloS one ;16 (5):e0245031.
  28. Feng YA, Guo Y, Pain L, Lathrop GM, Laprise C, Moffatt MF, Cookson WO, Liang L. 2021. Estimating cell-type-specific DNA methylation effects in heterogeneous cellular populations. Epigenomics ;13 (2):87-97.
  29. Xu CJ, Gruzieva O, Qi C, et al. 2021. Shared DNA methylation signatures in childhood allergy: The MeDALL study. J Allergy Clin Immunol ;147 (3):1031-1040.
  30. Bélanger É, Madore AM, Boucher-Lafleur AM, Simon MM, Kwan T, Pastinen T, Laprise C. 2020. Eosinophil microRNAs Play a Regulatory Role in Allergic Diseases Included in the Atopic March. Int J Mol Sci ;21 (23).
  31. Fois A, Boucher-Lafleur AM, Thompson Legault J, Renaud C, Morin C, Des Rosiers C, Coderre L, Laprise C, Lesage S. 2020. Humoral responses to the measles, mumps and rubella vaccine are impaired in Leigh Syndrome French Canadian patients. PLoS One ;15 (10):e0239860.
  32. Asai Y, Martino D, Eiwegger T, et al. 2020. Phenotype consensus is required to enable large-scale genetic consortium studies of food allergy. Allergy ;75 (9):2383-2387.
  33. Bchetnia M, Allard JP, Boucher-Lafleur AM, Cruz Marino T, Dupéré A, Powell J, McCuaig C, Bernier M, Laprise C. 2020. Severe epidermolysis bullosa simplex phenotype caused by codominant mutations p.Ile377Thr in keratin 14 and p.Gly138Glu in keratin 5. Exp Dermatol ;29 (10):961-969.
  34. Hoang TT, Sikdar S, Xu CJ, et al. 2020. Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study. Eur Respir J ;56 (3).
  35. Moreau C, Rébillard RM, Wolking S, Michaud J, Tremblay F, Girard A, Bouchard J, Minassian B, Laprise C, Cossette P, Girard SL. 2020. Polygenic risk scores of several subtypes of epilepsies in a founder population. Neurol Genet ;6 (3):e416.
  36. Simard M, Madore AM, Girard S, Waserman S, Duan Q, Subbarao P, Sears MR, Moraes TJ, Becker AB, Turvey SE, Mandhane PJ, Morin C, Bégin P, Laprise C. 2021. Polygenic risk score for atopic dermatitis in the Canadian population. J Allergy Clin Immunol ;147 (1):406-409.
  37. Madore AM, Pain L, Boucher-Lafleur AM, Morin A, Meloche J, Simon MM, Ge B, Kwan T, Cheung WA, Pastinen T, Laprise C. 2020. Asthma-associated polymorphisms in 17q12-21 locus modulate methylation and gene expression of GSDMA in naïve CD4(+) T cells. J Genet Genomics ;47 (3):171-174.
  38. Harding T, Milot E, Moreau C, Lefebvre JF, Bournival JS, Vézina H, Laprise C, Lalueza-Fox C, Anglada R, Loewen B, Casals F, Ribot I, Labuda D. 2020. Historical human remains identification through maternal and paternal genetic signatures in a founder population with extensive genealogical record. Am J Phys Anthropol. epub ahead of print.
  39. Meloche J, Brunet V, Gagnon P-A, Bouchard J-B, Nadaf J, Majewski J, Morin C, Laprise C.2020. Exome Sequencing Study of Partial Agenesis of the Corpus Callosum in Men With Developmental Delay, Epilepsy, and Microcephaly. Mol Genet Genomic Med. 8(1):e992.
  40. Sugier PE, Sarnowski C, Granell R, Laprise C, Ege MJ, Margaritte-Jeannin P, Dizier MH, Minelli C, Moffatt MF, Lathrop M, Cookson WOCM, Henderson AJ, von Mutius E, Kogevinas M, Demenais F, Bouzigon E. 2019. Genome-wide interaction study of early-life smoking exposure on time-to-asthma onset in childhood. Clin Exp Allergy. 49(10):1342-51.
  41. Mukaneza Y, Cohen A, Rivard ME, Tardif J, Deschênes S, Ruiz M, Consortium L, Laprise C, Des Rosiers C, Coderre L. 2019. mTORC1 is required for expression of LRPPRC and cytochrome c oxidase but not HIF-1α in Leigh Syndrome French Canadian Type Patient Fibroblasts. Am J Physiol Cell Physiol. epub ahead of print
  42. Reese SE, Xu CJ, den Dekker HT & al. 2018. Epigenome-wide Meta-analysis of DNA Methylation and Childhood Asthma. J Allergy Clin Immunol.  Dec;143(6):2062-2074
  43. Dizier MH, Margaritte-Jeannin P, Pain L, Sarnowski C, Brossard M, Mohamdi H, Lavielle N, Babron MC, Just J, Lathrop M, Laprise C,** Bouzigon E,** Demenais F,* Nadif R.* 2019. Interactive effect between ATPase-related genes and early-life tobacco smoke exposure on bronchial hyper-responsiveness detected in asthma-ascertained families. J Med Genet. 74(3):254-60
  44. Morin A, Madore AM, Kwan T, Ban M, Partanen J, Rönnblom L, Syvänen AC, Sawcer S, Stunnenberg H, Lathrop M, Pastinen T, Laprise C. 2019. Exploring rare & low-frequency variants in the Saguenay-Lac-Saint-Jean population identified genes associated with asthma and allergy traits.Eur J Hum Genet. 27(1):90-101
  45. Larouche M, Gagné-Ouellet V, Boucher-Lafleur AM, Larose MC, Plante S, Madore AM, Laviolette M, Flamand N, Chakir J, Laprise C. 2018. Methylation profiles of IL33 and CCL26 in bronchial epithelial cells are associated with asthma. Epigenomics. 10(12):1555-1568
  46. Li J, Zhu X, Yu K, Jiang H, Zhang Y, Wang B, Liu X, Deng S, Hu J, Deng Q, Sun H, Guo H, Zhang X, Chen W, Yuan J, He M, Bai Y, Han X, Lin B, Liu C, Guo Y, Zhang B, Zhang Z, Hu FB, Gao W, Li L, Lathrop M, Laprise C, Liang L, Wu T.2018. Exposure to Polycyclic Aromatic Hydrocarbons and Accelerated DNA Methylation Aging. Environ Health Perspect. 126(6) :067005
  47. Sugier PE, Brossard M, Sarnowski C, Vaysse A, Morin A, Pain L, Margaritte-Jeannin P, Dizier MH, Cookson WOCM, Lathrop M, Moffat MF, Laprise C, Demenais F, Bouzignon E. 2018. A novel role for ciliary function in atopy: ADGRV1 and DNAH5 J Allergy Clin Immunol. 141(5):1659-1667.e11
  48. Xu CJ, Söderhäll C, Bustamante M, et al.2018. DNA methylation in childhood. DNA methylation in childhood asthma: an epigenome-wide meta-analysis. Lancet Resp Med. 6(5):379-388
  49. Margaritte-Jeannin P, Babron MC, Laprise C, Lavielle N, Sarnowski C, Brossard M, Moffat M, Gagné-Ouellet V, Etcheto A, Lathrop M, Just J, Cookson WO, Bouzignon E, Demenais F, Dizier MH. 2018. The COL5A3 and MMP9 genes interact in eczema susceptibility. Clin Exp Allergy. 48(3):297-305
  50. Ho B, Greenlaw K, Tuwaijri AA, Moussette S, Martinez F, Giorgio E, Brusco A, Ferrero G, Linhares N, Valadares E, Svartman M, Kalscheuer V, Criado GR, Laprise C, Greenwood C, Naumova A.2018. X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells. Biology of Sex Differences. 9(1):10
  51. Demenais F, Margaritte-Jeannin P, Barnes KC et al. 2018. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 50(1):42-53
  52. Mühleisen TW, Reinbold CS, Forstner AJ, et al. 2017. Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder. J Affect Disord. 228:20-25
  53. Poon AH, Choy DF, Chouiali F, Ramakrishnan RK, Mahboub B, Audusseau S, Mogas A, Harris JM, Arron JR, Laprise C and Hamid Q. 2017. Increased autophagy-related 5 gene expression is associated with collagen expression in the airways of refractory asthmatics. Front Immunol. 8:355.
  54. Moussette S, Al Tuwaijri A, Kohan-Ghadr HR, Elzein S, Farias R, Bérubé J, Ho B, Laprise C, Goodyer CG, Rousseau S, Naumova AK. 2017. Role of DNA methylation in expression control of the IKZF3-GSDMA region in human epithelial cells. PLoS One. 12(2):e0172707.
  55. Forstner AJ, Hecker J, Hofmann A, et al.2017. Identification of shared risk loci and pathways for bipolar disorder and schizophrenia. PLoS One. 12(2):e0171595.
  56. Morin A, Laviolette M, Pastinen T, Boulet LP, Laprise C. 2017. Combining -omics data to identify genes associated with allergic rhinitis. Clin Epigenetics. 9:3.
  57. Chen W, Forno E, Wang T, Pino-Yanez M, Liang L, Yan Q, Hu D, Weeks D E., Baccarelli A, Acosta-Perez E, Han Y, Boutaoui N, Laprise C, A. Davies G, M. Hopkin J, F. Moffatt M,  Cookson W, Canino G, Burchard G. E, Celedón JC. 2017. An Epigenome-wide Association Study of Total Serum Immunoglobulin E in Hispanic Children. J Allergy Clin Immunol.140(2):571-577.
  58. Sarnowski C, Sugier PE, Granell R, Jarvis D, Dizier MH, Ege M, Imboden M, Laprise C, K. Khusnutdinova E, Freidin B, O.C. Cookson W, Phil D, Moffatt M, Lathrop M, Siroux V, M. Ogorodova L, S. Karuna A, James A, e M. Probst-Hensch N, von Mutius E, Pin I, Kogevinas M, Henderson AJ, Demenais F, Bouzigon E.2016. Identification of a new locus at 16q12 associated with time-to-asthma onset.  J Allergy Clin Immunol. 138(4):1071-1080.
  59. Morin A, Kwan T, Ge B, Letourneau L, Ban M, Tandre K, Caron M, Sandling JK, Carlsson J, Bourque G, Laprise C, Montpetit A, Syvanen AC, Ronnblom L, Sawcer SJ, Lathrop MG, Pastinen T. 2016. Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells. BMC Med Genomics. 9(1):59.
  60. Sarnowski C, Laprise C, Malerba G, Moffatt M, Dizier MH, Morin A, Vincent Q, Rohde K, Esparza-Gordillo J, Margaritte-Jeannin P, Liang L, Lee YA, Bousquet J, Siroux V, Franco Pignatti P, Cookson W, Lathrop M, Pastinen T, Demenais F, Bouzigon E.2016. DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis. J Allergy Clin Immunol. 138(3):748-53.
  61. Madore AM, T. Vaillancourt V, Bouzigon E, Sarnowski C, Monier F, Dizier MH, Demenais F and Laprise C. 2016. Genes involved in interleukin-1 receptor type II activities are associated with asthma-related phenotypes. Allergy, Asthma & Immunology Research. 8(5):466-70. 
  62. Bérubé JC, Gaudreault N, Lavoie-Charland E, Sbarra L, Henry C, Madore AM, Paré PD, van den Berge M, Nickle D, Laviolette M, Laprise C, Boulet LP, Bossé Y. 2016. Identification of Susceptibility Genes of Adult Asthma in French Canadian Women. Can Respir J. 3564341.
  63. Dizier MH, Nadif R, Margaritte-Jeannin P, Barton SJ, Sarnowski C, Gagné-Ouellet V, Brossard M, Lavielle N, Just J, Lathrop M, Holloway JW, Laprise C, Bouzigon E, Demenais F. 2016. Interaction between the DNAH9 gene and early smoke exposure in bronchial hyperresponsiveness. Eur Respir J. 47(4):1072-81.
  64. Al Tuwaijri A, Gagné-Ouellet V, Madore AM, Laprise C, K. Naumova A. 2016. Local Genotype Influences DNA Methylation at Two Asthma-Associated Regions 5q31 and 17q21 in a Founder Effect Population. J Med Genet. 53(4):232-41.
  65. Bchetnia M, Lacroix J, Farez T, Larouche M, Powell J, McCuaig C, Dupéré A, Morin C, Legendre-Guillemin V, Laprise C. 2016. Reduction of keratin aggregates in epidermolysis bullosa simplex keratinocytes after pretreatment with trimethylamine N-oxide. Exp Dermatol. 25(3):229-30.
  66. Forstner AJ, Hofmann A, et al. Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder. Transl Psychiatry 5: e678.
  67. Marenholz I, Esparza-Gordillo J, Rüschendorf F, Bauerfeind A, Strachan D, Spycher B, Baurecht H, Margaritte-Jeannin P, Sääf A, Kerkhof M, Ege M, Baltic S et al. 2015. Meta-analysis identifies 7 susceptibility loci involved in the atopic march. Nat Commun. 6:8804.
  68. Thompson Legault J, Stittmatter L, Tardif J, Sharma R, T. Vaillancourt V, Aubut C, Boucher G, Clish B, Cyr D, Daneault C, Water J. P, The LSFC Consortium, Vachon L, Morin C, Laprise C, Rioux D. J,Mootha K. V, Des Rosiers C.2015. A metabolic signature of mitochondrial dysfunction revealed through a monogenic form of Leigh Syndrome. Cell Rep. 13(5):981-9.
  69. Gagné-Ouellet V, Guay SP, Boucher-Lafleur AM, Bouchard L, Laprise C. 2015. DNA methylation signature of interleukin 1 receptor type II in asthma. Clin Epigenetics. 7(1):80.
  70. Liang L, Willis-Owen SA, Laprise C, Wong KC, Davies GA, Hudson TJ, Binia A, Hopkin JM, Yang IV, Grundberg E, Busche S, Hudson M, Rönnblom L, Pastinen TM, Schwartz DA, Lathrop GM, Moffatt MF, Cookson WO. 2015. An epigenome-wide association study of total serum immunoglobulin E concentration. Nature. 520(7549):670-4.
  71. Laprise C, Bouzigon E. 2014. Understand the allergic diseases biology using human populations by a transdisciplinary approach. Curr Opin Allergy Clin Immunol. 14(5):379-80.
  72. Dizier MH, Margaritte-Jeannin P, Madore AM, Moffatt M, Brossard M, Lavielle N, Sarnowski C, Just J, Cookson W, Lathrop M, Laprise C, Bouzigon E, Demenais F.2014. The nuclear factor I/A (NFIA) gene is associated with the asthma plus rhinitis phenotype. J Allergy Clin Immunol.
  73. Gauvin H, Moreau C, Lefebvre JF, Laprise C, Vézina H, Labuda D, Roy-Gagnon MH.2013. Genome-wide patterns of identity-by-descent sharing in the French Canadian founder population. Eur J Hum Genet.
  74. Laprise C. 2014. The Saguenay-Lac-St-Jean asthma familial collection : the genetics of asthma in a young founder population. Genes and Immunity.15(4):247-55.
  75. Mühleisen T, Leber M,et al.2014. Genome-wide association study reveals two new risk loci for bipolar disorder. Nature Communications. 5:3339.
  76. Bissonnette EY, Madore AM, Chakir J, Laviolette M, Boulet LP, Hamid Q, Bergeron C, Maghni K, Laprise C.2013. Fibrolast growth factor-2 is s sputum rmeodeling biomarker of severe asthma. J Asthma.
  77. Laprise C, Bouzigon E. 2013. The genetics of asthma and allergic diseases: pieces of the puzzle are starting to come together. Curr Opin Allergy Clin Immunol. 13(5):461-2.
  78. Madore AM, Vaillancourt VT, Asai Y, Alizadehfar R, Ben-Shoshan M, Michel DL, Kozyrskyj AL, Becker A, Chang-Yeung M, Daley D, Clarke AE, Hull P, Sandford AJ and Laprise C.2013. HLA-DQB1 is a genetic determinant for peanut allergy. Eur J Hum Genet. 21(10):1181-4
  79. Naumova AK, Al Tuwaijri A, Morin A, Vaillancout VT, Madore AM, Berlivet S, Kohan-Ghadr HR, Moussette S, Laprise C. 2013. Sex- and age-dependent DNA methylation at the 17q12-q21 locus associated with childhood asthma. Hum Genet. 132(7):811-22.
  80. Bchetnia M, Farez T, Duval J, Leclerc G, Dupérée A, Powell J, McCuaig C, Morin C, Legendre-Guillemin V, Laprise C. 2013. Microarray analysis of epidermolysis bullosa simplex-mottled pigmentation variant. J Dermatol Sci. 69 (1):80-2.
  81. Daley D, Park JE, He JQ, Yan J, Akhabir L, Stefanowicz D, Becker AB, Chan-Yeung M, Bossé Y, Kozyrskyj AL, James AL, Musk AW, Laprise C, Hegele RG, Paré PD, Sandford AJ. 2012. Associations and interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related phenotypes. J Allergy Clin Immunol. 130(6):1284-93.
  82. Vaillancourt VT, Bordeleau M, Laviolette M, Laprise C. 2012. From expression pattern to genetic association in asthma related phenotypes. BMC Res Notes. 5:630.
  83. Bouzigon E, Laprise C.2012. Comprehensive integration of genetic and environmental determinants to increase knowledge of the allergic diseases. Curr Opin Allergy Clin Immunol. 12(5):447-8.
  84. Morin A, Brook JR, Duchaine C, Laprise C.2012. Association study of genes associated to asthma in a specific environment, in an asthma familial collection located in a rural area influenced by different industries.Int J Environ Res Public Health. 9(8):2620-35.
  85. Verlaan DJ, Ouimet M, Adoue V, Sirois-Gagnon D, Larivière M, Ge B, Beaulieu P, Dias J, Lam KC, Koka V, Laprise C, Pastinen T, Sinnett D. 2012. Promoter polymorphisms in CHI3L1 are associated with asthma. J Allergy Clin Immunol. 130(2):533-5.
  86. Dizier MH, Margaritte-Jeannin P, Madore AM, Esparza-Gordillo J, Moffatt M, Corda E, Monier F, Guilloud-Bataille M, Franke A, Weidinger S, Annesi-Maesano I, Just J, Pin I, Kauffmann F, Cookson W, Lee YA, Laprise C, Lathrop M, Bouzigon E, Demenais F. 2012. The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma. J Allergy Clin Immunol. 129(6):1547-53.
  87. Poon A, Eidelman D, Laprise C, Hamid Q.2012. ATG5, autophagy and lung function in asthma. Autophagy. 8(4).
  88. Poon AH, Chouiali F, Tse SM, Litonjua AA, Hussain SN, Baglole CJ, Eidelman DH, Olivenstein R, Martin JG, Weiss ST, Hamid Q, Laprise C.2012. Genetic and histologic evidence for autophagy in asthma pathogenesis. J Allergy Clin Immunol. 129(2):569-71.
  89. Lavoie JP, Lefebvre-Lavoie J, Leclere M, Lavoie-Lamoureux A, Chamberland A, Laprise C, Lussier J.2012. Profiling of differentially expressed genes using suppression subtractive hybridization in an equine model of chronic asthma. PLoS One. 7(1):e29440.
  90. Bchetnia M, Tremblay M-L, Leclerc G, Dupérée A, Powell J, McCuaig C, Morin C, Legendre-Guillemin V, Laprise C. 2011. Expression signature of epidermolysis bullosa simplex. Hum Genet.
  91. Laprise C, Bouzigon E.2011. To define the biological nature of asthma. Curr Opin Allergy Clin Immunol.
  92. Poon A, Litonjua AA, Laprise C. 2011. Relevance and implication of genetic determinants to asthma pathophysiology. Curr Opin Allergy Clin Immunol.
  93. Legault J, Perron T, Mshvildadze V, Girard-Lalancette K, Perron S, Laprise C, Sirois P, Pichette A.2011. Antioxidant and Anti-Inflammatory Activities of Quercetin 7-O-β-D-Glucopyranoside from the Leaves of Brasenia schreberi. J Med Food.
  94. Coutinho M, Encarnação M, Gomes R, Da Silva Santos L, Martins S, Sirois-Gagnon D, Bargal R, Filocamo M, Raas-Rothschild A, Tappino B, Laprise C, Cury G, Schwartz I, Artigalás O, Prata M, Alves S. 2011. Origin and spread of a common deletion causing mucolipidosis type II: insights from patterns of haplotypic diversity. Clin Genet. 80(3):273-80.
  95. Roy-Gagnon MH, Moreau C, Bherer C, St-Onge P, Sinnett D, Laprise C, Vézina H, Labuda D. 2011. Genomic and genealogical investigation of the French Canadian founder population structure. Hum Genet.
  96. Sirois-Gagnon D, Chamberland A, Perron S, Brisson D, Gaudet D, Laprise C.2011. Association of Common Polymorphisms in the Fractalkine Receptor (CX3CR1) With Obesity. Obesity (Silver Spring). 19(1):222-7.
  97. Madore AM, Perron S, Turmel V, Laviolette M, Bissonnette EY, Laprise C.2010.  Alveolar macrophages in allergic asthma: an expression signature characterized by heat shock protein pathways. Hum Immunol. 71(2):144-50.
  98. Boulet LP, Turcotte H, Prince P, Lemière C, Olivenstein R, Laprise C, Larivée P, Bégin P, Laviolette M. 2009. Benefits of low-dose inhaled fluticasone on airway response and inflammation in mild asthma. Respir Med. 103(10):1554-63. Epub 2009 Aug 18.
  99. Verlaan DJ, Berlivet S, Hunninghake GM, Madore AM, Larivière M, Moussette S, Grundberg E, Kwan T, Ouimet M, Ge B, Hoberman R, Swiatek M, Dias J, Lam KC, Koka V, Harmsen E, Soto-Quiros M, Avila L, Celedón JC, Weiss ST, Dewar K, Sinnett D, Laprise C, Raby BA, Pastinen T, Naumova AK.2009. Allele-Specific Chromatin Remodeling in the ZPBP2/GSDMB/ORMDL3 Locus Associated with the Risk of Asthma and Autoimmune Disease. Am J Hum Genet. 85(3):377-93.
  100. He JQ, Hallstrand TS, Knight D, Chan-Yeung M, Sandford A, Tripp B, Zamar D, Bossé Y, Kozyrskyj AL, James A, Laprise C, Daley D.2009. A thymic stromal lymphopoietin gene variant is associated with asthma and airway hyperresponsiveness. J Allergy Clin Immunol. 124(2):222-9.
  101. Chamberland A, Madore AM, Tremblay K, Laviolette M, Laprise C.2009. A comparison of two microarray experiments to define asthma transcriptome. Exp Lung Res. 35(5):399-410.
  102. Daley D, Lemire M, Akhabir L, Chan-Yeung M, He J, McDonald T, Sandford A, Stefanowicz D, Tripp B, Zamar D, Bossé Y, Ferretti V, Montpetit A, Tessier M-C, Becker A, Kozyrskyj AL, Beilby J, McCaskie PA, Musk B, Warrington N, James A, Laprise C, Palmer L, Paré PD, Hudson TJ. 2009. Analyses of associations with asthma in four asthma population samples from Canada and Australia. Human Genetics. 125(4):445-59.
  103. Tewfik MA, Bossé Y, Lemire M, Hudson TJ, Vallée-Smejda S, Al-Shemari H, Laprise C, Desrosiers M.2009. Polymorphisms in the toll-like receptor signaling pathway at the level of the interleukin-1 receptor-associated kinase-4 gene are associated with total serum IgE level. Allergy. 64(5):746-53.
  104. Chamberland A, Tremblay N, Audet M, Gilbert B, Pérusse L, Vohl M-C, Laprise C.2009. Association study between candidate genes and obesity-related phenotypes using a sample of lumberjacks. Public Health Genomics. 12(4):253-8.
  105. Bossé Y, Lemire M, Poon AH, Daley D, He JQ, Sandford A, White JH, James AL, Musk AW, Palmer LJ, Raby BA, Weiss ST, Kozyrskyj AL, Becker A, Hudson TJ, Laprise C. 2009. Asthma and genes encoding components of the vitamin D pathway.Respir Res. 10:98.
  106. Zhang J, Daley D, Akhabir L, Stefanowicz D, Chan-Yeung M, Becker AB, Laprise C, Paré PD, Sandford AJ. 2009. Lack of association of TIM3 polymorphisms and allergic phenotypes. BMC Med Genet. 10:62.
  107. Tremblay K, Daley D, Chamberland A, Lemire M, Montpetit A, Laviolette M, James A, Chang-Yeung M, Musk AW, Backer A, Sandford AJ, Paré PD, Hudson TJ, Laprise C. 2008. Genetic variation in immune signaling genes differentially expressed in asthmatic lung tissues. J Allergy Clin Immunol. 122(3):529-36.
  108. Madore A-M, Prévost C, Dorfman R, Durie P, Zielenski J, Laprise C.2008.  Distribution of CFTR mutations in Saguenay–Lac-Saint-Jean: proposal of a panel of mutations for population screening. Genet Med. 10(3):201-6.
  109. Plante M, Lepage P, Brunet S, Roquis D, Claveau S, Hudson TJ, Morin C, Laprise C. 2008. Mucolipidosis type II : A unique causal mutation in the N-acetylglucosamine-1-phosphotransferase gene (GNPTAB) in a French Canadian Founder Population. Clin Genet. 73(3):236-44.
  110. Madore A-M, Tremblay K, Hudson TJ, Laprise C. 2008. Replication of an association between 17q21 SNPs and asthma in a French-Canadian familial collection. Hum Genet.123(1):93-5.
  111. Tremblay K, Potvin C, Lemire M, Salesse C, Tremblay A, Rabi B, Hudson TJ, Perez-Iratxeta C, Andrade-Navarro MA, Laprise C.2008. Genes to diseases (G2D) computational method to identify asthma candidate genes. PLoS ONE. 3(8):e2907.
  112. Bouhali T, Brisson D, Saint-Pierre J, Tremblay G, Perron P, Laprise C, Vohl MC, Vissers MN, Hutten BA, Després JP, Kastelein JJ, Gaudet D. 2008. Low plasma adiponectin concentration exacerbates the risk of premature coronary artery disease in familial hypercholesterolemia. Atherosclerosis. 196(1):262-9.
  113. Bégin P, Tremblay K, Daley D, Lemire M, Claveau S, Salesse C, Kacel S, Montpetit A, Becher A, Sandford AJ, Paré P, Hudson TJ, Laprise C. 2007. Association of Urokinase-type plasminogen activator with asthma. Am J Respir Crit Care Med. 175(11):1109-16.
  114. Boulet LP, Hamid Q; Bacon SL, Bergeron C, Boulet LP, Chen Y, Dixon AE, Ernst P, Hamid Q, Holguin F, Irvin CG, Kimoff RJ, Komakula S, Laprise C, Lavoie KL, Shore SA, Teodorescu M, Vohl MC. 2007. Symposium on obesity and asthma – November 2, 2006. Can Respir J. 14(4):201-8. PMID: 17551594.
  115. Dufour D, Pichette A, Mshvildadze V, Bradette-Hébert M-E, Lavoie S, Longtin A, Laprise C, Legault J. 2006. Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Ledum groenlandicum Retzius. J Ethnopharmacol.
  116. Madore A-M, Houde L, Vézina H,Vohl MC, Pérusse L, Mior N, Connelly PW, Laberge C, Hudson TJ, Gaudet D, Laprise C. 2007. Contribution of hierarchical clustering techniques to the modeling of the geographic distribution of genetic polymorphisms associated with chronic inflammatory diseases in the Quebec population. Community Genet. 10(4):218-26.
  117. Tremblay K, Provost V, Lemire M, Pastinen T, Renaud Y, Pagé N, Sandford A, Hudson TJ, Laviolette M and Laprise C. 2006. Association study between the CX3CR1 gene and asthma: a new candidate gene for asthma.Genes Immun. 7(8):632-9.
  118. Boulet LP, Prince P, Turcotte H, Lemiere C, Olivenstein R, Laprise C, Larivee P, Begin P, Laviolette M. 2006. Clinical features and airway inflammation in mild asthma versus asymptomatic airway hyperresponsiveness. Respir Med ; 100 : 292-299.
  119. Poon AH, Laprise C,Lemire M, Hudson TJ, Schurr E. 2005. NRAMP1 is not associated with asthma, atopy, and serum immunoglobulin E levels in the French Canadian population. Genes Immun. 6(6):519-27.
  120. Laprise C, Poon A, Lemire M, Montpetit A, Schurr E, Hudson TJ.2004. Association of Vitamin D Receptor Genetic Variants with Susceptibility to Asthma and Atopy. Am J Respir Crit Care Med. 170(9):967-73.
  121. Lemire M, Roslin NM, Laprise C, Hudson TJ, Morgan K. 2004. Transmission-ratio distortion and allele sharing in affected sib pairs: a new linkage statistic with reduced bias, with application to chromosome 6q25.3. Am J Hum Genet. 75(4):571-86.
  122. LaitinenT , Polv iA, Rydman P, Vendelin J, Mäkelä S, Pulkkinen V, Salmikangas P, Rehn M, Pirskanen A, Rautanen A, Zucchelli M, Gullstén H, Petäys T, Haahtela T, Laitinen A, Laprise C, Hudson TJ, Laitinen LA, Kere J. 2004. Characterization of a common susceptibility locus for asthma-related traits. Science ;304 (5668):300-4.
  123. Laprise C, Sladek R, Ponton A, Bernier M-C, Hudson TJ, Laviolette M. 2004. Functional classes of bronchial mucosa genes that are differentially expressed in asthma. BMC Genomics. 5(1):21.
  124. Raby BA, Klimecki W.T, Laprise C, Renaud Y, Faith J, Lemire M, Greenwood CM, Lange C, Palmer L, Lazarus R, Vercelli D, Kwiatkowski DJ, Silverman E, Martinez F, Hudson TJ, Weiss ST.2002. Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes. Am J Human Genet. 166(11): 1449-56.
  125. Laitinen T, Daly MJ, Rioux J, Kauppi P, Laprise C, Petäys T, Green T, Cargill M, Haahtela T, Lander ES, Laitinen LA, Hudson TJ & Kere J. 2001. A susceptibility locus for asthma-related traits on chromosome 7 revealedby a genome-wide scan in a founder population. Nat Genet. 28(1):87-91.
  126. Laprise C, Boulet L-P, Morissette J, Winstall E, Raymond V. 2000. Evidence for linkage and association between atopy, airway hyperresponsiveness and the Glu237Gly of the ß subunit of the high-affinity receptor for immunoglobulin E (FcεRI-β). Immunogenetics. 51(8-9):695-702.
  127. Laprise C, Laviolette M, Boutet M, Boulet L-P. 1999. Asymptomatic airway hyperresponsiveness: relationships with airway inflammation and remodeling. Eur Respir J. 14(1) : 63-73.
  128. Laprise C, Boulet L-P. 1997. Asymptomatic airway hyperresponsiveness: A three-year follow-up. Am J Respir Crit Care Med. 156: 403-409.
  129. Boulet L-P, Turcotte H, Laprise C, Lavertu C, Bédard P-M, Lavoie A, Hébert J.1997. Comparative degree and type of sensitization to common indoor and outdoor allergens in subjects with allergic rhinitis and/or asthma. Clin Exp Allergy ; 27: 52-59.
  130. Laprise C, Boulet L-P. 1996. Airway responsiveness and atopy in families of patients with asthma. Clin Invest Med. 19(6): 461-469.
  131. Laprise C, Boulet L-P. 1996. Magnitude and determinants of short-term tachyphylaxis to methacholine in subjects with symptomatic or asymptomatic airway hyperresponsiveness and in normal controls. Respiration. 63(5):304-8.

Reviews

Reviews

  1. Bchetnia M, Powell J, McCuaig C, Boucher-Lafleur AM, Morin C, Dupérée A, Laprise C. 2024. Pathological mechanisms involved in epidermolysis bullosa simplex: current knowledge and therapeutic perspectives. International Journal of Molecular Sciences. 31;25(17):9495.
  2. Nadeau-Tremblay S, Boily É, Brault MC, Chevrette T, Jacob É, Langelier MÈ, Laprise C, Mercure C, Pulido L. 2023. Supporting the emergence of outdoor teaching practices in primary school settings: a literature review. Education 3-13. 1: 13.
  3. Bchetnia M, Bouchard L, Mathieu J, Campeau P, Morin C, Brisson D, Laberge AM, Vézina H, Gaudet D, Laprise C. Genetic burden linked to founder effects in Saguenay-Lac-Saint-Jean illustrates the importance of genetic screening test availability. J Med Genet 2021.
  4. Bchetnia M, Girard C, Duchaine C, Laprise C. The outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): A review of the current global status. J Infect Public Health 2020;13 (11):1601-1610.
  5. Hudon Thibault AA, Laprise C. Cell specific DNA methylation signatures in asthme. Genes (Basel). 2019 Nov 15;10(11):932.
  6. Simard M, Laprise C, Girard SL. Impact of Paternal Age at Conception on Human Health. Clin Chem. 2019 Jan;65(1):146-152
  7. Boulay ME, Morin A, Laprise C, Boulet LP. Asthma and rhinitis: what is the relationship? Curr Opin Allergy Clin Immunol. 2012 Oct;12(5):449-54.
  8. Poon AH, Gong L, Brasch-Andersen C, Litonjua AA, Raby BA, Hamid Q, Laprise C, Weiss ST, Altman RB, Klein TE. Very important pharmacogene summary for VDR. Pharmacogenet Genomics. 2012 May 14.
  9. Poon AH, Eidelman DH, Martin JG, Laprise C, Hamid Q. Pathogenesis of severe asthma. Clin Exp Allergy. 2012 May;42(5):625-37.
  10. Poon A, Litonjua AA, Laprise C. Relevance and implication of genetic determinants to asthma pathophysiology. Curr Opin Allergy Clin Immunol. 2011 Aug 4.
  11. Madore A-M, Laprise C. Immunological and genetic aspects of asthma and allergy. Journal of Asthma and Allergy. 2010; 3:107-121.
  12. Boulet LP, Chakir J, Dubé J, Laprise C, Boutet M, Laviolette M. Airway inflammation and structural changes in airway hyper-responsiveness and asthma: an overview. Can Respir J. 1998 Jan-Feb;5(1):16-21.

Collaborations

Collaborations

  1. Krzeczkowski JE, Lau A, Fitzpatrick J, Tamana S, Smithson L, de Souza R, Kozyrskyj AL, Lefebvre D, Becker AB, Subbarao P, Turvey SE, Pei J, Schmidt LA, Sears MR, Van Lieshout RJ, Mandhane PJ; CHILD Study Investigators. Maternal Metabolic Complications in Pregnancy and Offspring Behavior Problems at 2 Years of Age. Matern Child Health J. 2019 Jun;23(6):746-55
  2. Matenchuk BA, Tamanaa SK, Lou YWW. Lefebvre DL, Sears MR, Becker AB, Azad MB, Moraes TJ, Turvey SE, Subbarao P, Kozyrskyja AL, Mandhanea PJ, CHILD Study Investigators. Prenatal Depression and Birth Mode Sequentially Mediate Maternal Education’s Influence on Infant Sleep Duration. Sleep Medicine. 2019
  3. Cusack L, Sbihi H, Larkin A, Chow A, Brook JR, Moraes T, Mandhane PJ, Becker AB, Azad MB, Subbarao P, Kozyrskyj A, Takaro TK, Sears MR, Turvey SE, Hystad P; CHILD Study Investigators. Residential green space and pathways to term birth weight in the Canadian Healthy Infant Longitudinal Development (CHILD) Study. Int J Health Geogr. 2018 Dec 4;17(1):43 Jan 29; in press
  4. Dharma C, Lefebvre DL, Tran MM, Lu Z, Lou WYW, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Azad MB, Sears MR; CHILD Study Investigators. Diagnosing atopic dermatitis in infancy: Questionnaire reports vs criteria-based assessment. Paediatr Perinat Epidemiol. 2018 Nov;32(6):556-567
  5. Azad MB, Vehling L, Chan D, Klopp A, Nickel NC, McGavock JM, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Taylor MS, Lefebvre DL, Sears MR, Subbarao P; CHILD Study Investigators. Infant Feeding and Weight Gain: Separating Breast Milk From Breastfeeding and Formula From Food. Pediatrics. 2018 Oct;142(4)
  6. Tun MH, Tun HM, Mahoney JJ, Konya TB, Guttman DS, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Brook JR, Lou W, Takaro TK, Scott JA, Kozyrskyj AL; CHILD Study Investigators. Postnatal exposure to household disinfectants, infant gut microbiota and subsequent risk of overweight in children. CMAJ. 2018 Sept 17;190(37): E1097–E1107
  7. Forbes JD, Azad MB, Vehling L, Tun HM, Konya TB, Guttman DS, Field CJ, Lefebvre D, Sears MR, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Subbarao P, Scott JA, Kozyrskyj AL; CHILD Study Investigators. Association of Exposure to Formula in the Hospital and Subsequent Infant Feeding Practices With Gut Microbiota and Risk of Overweight in the First Year of Life. JAMA Pediatr. 2018 Juin 4; epub ahead of print
  8. Miliku K, Robertson B, Sharma AK, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR; CHILD Study Investigators, Bode L, Azad M. Human milk oligosaccharide profiles and food sensitization among infants in the CHILD Study. Allergy. 2018 Mai 18; epub ahead of print
  9. Kamal M, Tamana SK, Smithson L, Ding L, Lau A, Chikuma J, Mariasine J, Lefebvre DL, Subbarao P, Becker AT, Turvey SE, Sears MR, CHILD Study Investigators, Pei J, Mandhane PJ. Phenotypes of sleep-disordered breathing symptoms to two years of age based on age of onset and duration of symptoms. Sleep Med. 2018 Mai 3;48:93-100
  10. Smithson L, Baird T, Tamana SK, Lau A, Mariasine J, Chikuma J, Lefebvre DL, Subbarao P, Becker AT, Turvey SE, Sears MR, CHILD Study Investigators, Beal DS, Pei J, Mandhane PJ. Shorter sleep duration is associated with reduced cognitive development at two years age. Sleep Med. 2018 Avril;48:131-139
  11. Tun HM, Bridgman SL, Chari R, Field CJ, Guttman DS, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Kozyrskyj AL; CHILD Study Investigators. Roles of Birth Mode and Infant Gut Microbiota in Intergenerational Transmission of Overweight and Obesity From Mother to Offspring. JAMA Pediatr. 2018 Avril 1;172(4):368-377
  12. Chan D, Goruk S, Becker A, Subbarao P, Mandhane P, Turvey S, Lefebvre D, Sears M, CHILD Study investigators, Field C, Azad M. Adiponectin, leptin and insulin in breast milk: associations with maternal characteristics and infant body composition in the first year of life. Int J Obes (Lond). 2018 Jan;42(1):36-43
  13. Dharma C, Lefebvre DL, Tran MM, Lou WYW, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Sears MR; CHILD Study Investigators. Patterns of allergic sensitization and atopic dermatitis from 1 to 3 years: Effects on allergic diseases. Clin Exp Allergy. 2018 Jan;48(1):48-59
  14. Tran MM, Lefebvre DL, Dharma C, Dai C, Lou WYW, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Sears MR; CHILD Study Investigators. Predicting the atopic march: Results from the Canadian Healthy Infant Longitudinal Development Study. J Allergy Clin Immunol. 2017 Nov 1;141(2):601-607.e8
  15. Koleva PT, Tun HM, Konya T, Guttman DS, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Kozyrskyj AL; CHILD Study Investigators. Sex-specific impact of asthma during pregnancy on infant gut microbiota. Eur Respir J. 2017 Nov 22;50(5)
  16. Klopp A, Vehling L, Becker AB, Subbarao P, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR; CHILD Study Investigators, Azad MB. Modes of Infant Feeding and the Risk of Childhood Asthma: A prospective Birth Cohort Study. J Pediatr. 2017 Nov; 190: 192-199.e2
  17. Tamana SK, Smithson L, Lau A, Mariasine J, Young R, Chikuma J, Lefebvre DL, Subbarao P, Becker AB, Turvey SE, Sears MR; CHILD Study Investigators, Pei J, Mandhane PJ. Parent-reported symptoms of sleep disordered breathing is associated with increased behavioral problems at 2 years of age: The Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort study. Sleep. 2017 Nov 1; zsx177
  18. Kang LJ, Koleva PT, Field CJ, Giesbrecht GF, Wine E, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Kozyrskyj A;, CHILD Study Investigators. Maternal depressive symptoms linked to reduced fecal Immunoglobulin A concentrations in infants. Brain Behav Immun. 2017 Oct 12;68:123-131
  19. Yasmin F, Tun HM, Konya TB, Guttman DS, Chari RS, Field CJ, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR; CHILD Study Investigators, Scott JA, Dinu I, Kozyrskyj AL. Cesarean section, formula feeding, and infant antibiotic exposure: separate and combined impacts on gut microbial changes in later infancy. Front Pediatr. 2017 Sep 26;5:200
  20. Cuillerier A, Honarmand S, Cadete VJJ, Ruiz M, Forest A, Deschênes S, Beauchamp C, LSFC Consortium, Charron G, Rioux JD, Des Rosiers C, Shoubridge EA, Burelle Y. Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion. Hum Mol Genet. 2017 Aug 15;26(13):3186-3201
  21. Tran MM, Lefebvre DL, Dai D, Dharma C, Subbarao P, Lou W, Azad MB, Becker AB, Mandhane PJ, Turvey SE, Sears MR; CHILD Study Investigators. Timing of food introduction and development of food sensitization in a prospective birth cohort. Pediatr Allergy Immunol. 2017 Aug 1; 28(5):471-7
  22. Graham C, Chooniedass R, Stefura WP, Becker AB, Sears MR, Turvey SE, Mandhane PJ, Subbarao P, CHILD Study Investigators, HayGlass KT. In vivo immune signatures of healthy human pregnancy: Inherently inflammatory or anti-inflammatory? PLOS one. 2017 Jun 21;12(6):e0177813.
  23. Azad MB, Vehling L, Lu Z, Dai D, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR; CHILD Study Investigators. Breastfeeding, maternal asthma and wheezing in the first year of life: a longitudinal birth cohort study. Eur Respir J. 2017 Mai;49(5): pii: 1602019
  24. Bridgman SL, Azad MB, Field CJ, Haqq AM, Becker AB, Mandhane PJ, Subbarao P, Turvey SE, Sears MR, Scott JA, Wishart DS, Kozyrskyj AL; CHILD Study Investigators. Fecal short-chain fatty acid variations by breastfeeding status in infants at 4 months: differences in relative versus absolute concentrations. Front Nutr. 2017 Apr 10;4:11
  25. Tun HM, Konya T, Takaro TK, Brook JR, Chari R, Field CJ, Guttman DS, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Kozyrskyj AL; CHILD Study Investigators. Exposure to household furry pets influences the gut microbiota of infant at 3-4 months following various birth scenarios. 2017 Apr 6;5(1):40.
  26. Bridgman SL, Konya T, Azad MB, Guttman DS, Sears MR, Becker AB, Turvey SE, Mandhane PJ, Subbarao P; CHILD Study Investigators, Scott JA, Field CJ, Kozyrskyj AL. High fecal IgA is associated with reduced Clostridium difficile colonization in infants. Microbes Infect. 2016 Sep;18(9):543-9.
  27. Azad MB, Sharma AK, de Souza RJ, Dolinsky VW, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Lefebvre DL, Sears MR; Canadian Healthy Infant Longitudinal Development Study Investigators. Association Between Artificially Sweetened Beverage Consumption During Pregnancy and Infant Body Mass Index. JAMA Pediatr. 2016 Jul;170(7):662-70
  28. Bolduc FV, Lau A, Rosenfelt CS, Langer S, Wang N, Smithson L, Lefebvre D, Alexander RT, Dickson CT, Li L, Becker AB, Subbarao P, Turvey SE, Pei J, Sears MR, Mandhane PJ; CHILD Study Investigators. Cognitive enhancement in infants associated with increased maternal fruit intake during pregnancy: results from a birth cohort study with validation in an animal model. EBioMedicine. 2016 Jun;8:331-40
  29. Azad MB, Konya T, Persaud RR, Guttman DS, Chari RS, Field CJ, Sears MR, Mandhane PJ, Turvey SE, Subbarao P, Becker AB, Scott JA, Kozyrskyj AL; CHILD Study Investigators. Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study. BJOG. 2016 May;123(6):983-93
  30. Bridgman SL, Konya T, Azad MB, Sears MR, Becker AB, Turvey SE, Mandhane PJ, Subbarao P; CHILD Study Investigators, Scott JA, Field CJ, Kozyrskyj AL.J Dev Orig Infant gut immunity: a preliminary study of IgA associations with breastfeeding.Health Dis. 2016 Feb;7(1):68-72.
  31. Takaro TK, Scott JA, Allen RW, Anand SS, Becker AB, Befus AD, Brauer M, Duncan J, Lefebvre DL, Lou W, Mandhane PJ, McLean KE, Miller G, Sbihi H, Shu H, Subbarao P, Turvey SE, Wheeler AJ, Zeng L, Sears MR, Brook JR; CHILD study investigators. The Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort study: assessment of environmental exposures. J Expo Sci Environ Epidemiol. 2015 Nov-Dec;25(6):580-92.
  32. Subbarao P, Anand SS, Becker AB, Befus AD, Brauer M, Brook JR, Denburg JA, HayGlass KT, Kobor MS, Kollmann TR, Kozyrskyj AL, Lou WY, Mandhane PJ, Miller GE, Moraes TJ, Pare PD, Scott JA, Takaro TK, Turvey SE, Duncan JM, Lefebvre DL, Sears MR; CHILD Study investigators. The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma. Thorax. 2015 Oct;70(10) :998-1000.
  33. Arrieta MC, Stiemsma LT, Dimitriu PA, Thorson L, Russell S, Yurist-Doutsch S, Kuzeljevic B, Gold MJ, Britton HM, Lefebvre DL, Subbarao P, Mandhane P, Becker A, McNagny KM, Sears MR, Kollmann T; CHILD Study Investigators, Mohn WW, Turvey SE, Finlay BB. Early infancy microbial and metabolic alterations affect risk of childhood asthma.Sci Transl Med. 2015 Sep 30;7(307):307ra152.
  34. Persaud RR, Azad MB, Chari RS, Sears MR, Becker AB, Kozyrskyj AL; the CHILD Study Investigators. Perinatal antibiotic exposure of neonates in Canada and associated risk factors: a population-based study. J Matern Fetal Neonatal Med. 2015 Jul;28(10):1190-5.
  35. Burelle Y, Bemeur C, Rivard ME, Thompson Legault J, Boucher G; LSFC Consortium, Morin C, Coderre L, Des Rosiers C. Mitochondrial vulnerability and increased susceptibility to nutrient-induced cytotoxicity in fibroblasts from leigh syndrome French canadian patients.PLoS One. 2015 Apr 2;10(3).
  36. Azad MB, Konya T, Guttman DS, Field CJ, Sears MR, HayGlass KT, Mandhane PJ, Turvey SE, Subbarao P, Becker AB, Scott JA, Kozyrskyj AL; CHILD Study Investigators. Infant gut microbiota and food sensitization: associations in the first year of life. Clin Exp Allergy. 2015 Mar;45(3):632-4.
  37. Moraes TJ, Lefebvre DL, Chooniedass R, Becker AB, Brook JR, Denburg J, HayGlass KT, Hegele RG, Kollmann TR, Macri J, Mandhane PJ, Scott JA, Subbarao P, Takaro TK, Turvey SE, Duncan JD, Sears MR, Befus AD; CHILD Study Investigators.The Canadian healthy infant longitudinal development birth cohort study: biological samples and biobanking. Paediatr Perinat Epidemiol. 2015 Jan;29(1):84-92.
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