Prof. Laprise is the holder of the Canada Research Chair in Environment and Genetics of Respiratory diseases and Allergy. Her research focuses on the identification of genetic risk factors associated with asthma. Furthermore, her research leverages the generation and integration of the “omics” data (i.e. genomic, genetic, transcriptomic, epigenetic) to better understand asthma pathogenesis.
In addition to her research interest in asthma, Prof. Laprise leads several projects on the identification of genetic determinants of orphan diseases, particularly those which are prevalent in the Saguenay-Lac St-Jean (SLSJ) population. Mucolipidosis type II, agenesis and dysgenesis of the corpus callosum, epidermolysis bullosa simplex, and lactic acidosis are some of these targeted orphan diseaes. The goals of her research on these orphan diseases are to identify causal mutations, understand disease etiologies, and develop effective therapies. Her laboratory is equipped with cutting-edge technology and provides an inspiring environment for genetic research.